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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO THE EDITOR Table of Contents   
Year : 1995  |  Volume : 6  |  Issue : 1  |  Page : 54
Authors reply

Consultant Nehprologist, King Fahd Specialist Hospital, P.O. Box 2290, Buraidah, Al-Gassim, Saudi Arabia

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How to cite this article:
Singh R G. Authors reply. Saudi J Kidney Dis Transpl 1995;6:54

How to cite this URL:
Singh R G. Authors reply. Saudi J Kidney Dis Transpl [serial online] 1995 [cited 2022 Jan 20];6:54. Available from: https://www.sjkdt.org/text.asp?1995/6/1/54/40901
We agree that there may be some differences in presentation, course, prognosis etc. in pediatric form of idiopathic focal segmental glomerulosclerosis (FSGS). However, the pediatric form of FSGS has not been recognized as a separate entity like minimal change glomerulonephritis. Secondly, regarding nephrotic range proteinuria it has been clearly stated as proteinuria of more than 3.5 g/day/1.73 m2for an adult. However, it will definitely be lower for an infant, since the body surface area is small. The level of hypertension was taken as defined by World Health Organisation. In pediatric age group, we have followed the task force recommendation for children [1] . Accordingly, the level of blood pressure quoted by the author falls in severe hypertension group. The statement regarding steroid resistant FSGS common in first year of life is not well documented, since as per existing practice, most of the infants are initially treated by steroids by most of the centers without proper tissue confirmation.

The lipids have been blamed in the pathogenesis of nephrotic syndrome [2] .However, it was not markedly raised in our cases. -Further in our study we have reported alternate days as single dose orally) and steroids with cyclophosphamide (2 mg/kg/ day orally). They were administered for eight and eight to 12 weeks respectively. However, some patients did require therapy for a longer duration especially the non-responder group similar to the experience of Banfi et al quoted in the communication by Akl. This data was not included in the present report.

   References Top

1.Report of the second task force on blood pressure control in children. Pediatrics 1987;79:l-25.  Back to cited text no. 1    
2.Moorehead JF. Lipid and the pathogenesis of kidney diseases in nephrology, by Hatano, et al. Vol. II, Tokyo, Springer Verlag, 1991;pp:165-81.  Back to cited text no. 2    

Correspondence Address:
R G Singh
Consultant Nehprologist, King Fahd Specialist Hospital, P.O. Box 2290, Buraidah, Al-Gassim
Saudi Arabia
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