Home About us Current issue Ahead of Print Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 997 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

CASE REPORT Table of Contents   
Year : 2002  |  Volume : 13  |  Issue : 2  |  Page : 163-170
Reversible Encephalopathy and Delirium in Patients with Chronic Renal Failure who had Received Ciprofloxacin

Renal Unit, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia

Correspondence Address:
Saeed MG Al-Ghamdi
Renal Unit, King Faisal Specialist Hospital and Research Center, Jeddah
Saudi Arabia
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 17660656

Rights and PermissionsRights and Permissions

We describe four patients with chronic renal failure (CRF) who developed significant neurotoxicity after receiving short-term ciprofloxacin. Three of them had developed encephalopathy with myoclonic jerks and one patient had delirium. All patients had advanced chronic renal failure (mean estimated creatinine clearance 16 6 ml/minute), although they were not yet on renal replacement therapy. The mean received dose of ciprofloxacin was 2150 1300 mg and symptoms started to appear after the first 24 hours of drug intake. Investigations ruled out other possible causes of these neurological presentations, and withdrawal of ciprofloxacin was followed by complete resolution, after a mean of 8.5 4 days. Advanced renal failure in all patients and underlying neurologic diseases in two patients may have predisposed them to the neurotoxicity. The report of these cases should help to draw the attention of clinicians to the potential occurrence of these adverse effects in patients with CRF.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded575    
    Comments [Add]    

Recommend this journal