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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2007  |  Volume : 18  |  Issue : 1  |  Page : 101-106
Hepatitis C virus infection in hemodialysis patients in Sudan: Two centers' report

1 Dr Salma Center for Dialysis and Kidney Transplantation, University of Khartoum, Sudan
2 Khartoum Teaching Hospital, Federal Ministry of Health, Khartoum, Sudan
3 Ahfad University for Women and Epidemiological Laboratory, Khartoum, Sudan

Correspondence Address:
M O Mekki
Khartoum Teaching Hospital, Federal Ministry of Health, Khartoum
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Source of Support: None, Conflict of Interest: None

PMID: 17237901

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Prevalence of HCV seropositivity among the hemodialysis population in Sudan is estimated to be around 34%. We undertook a cross sectional study in two major HD centers in Khartoum, Sudan for the prevalence of HCV seropositivity among the hemodialysis patients, during January to -March 2005. Testing for HCV antibodies was performed using 3 rd generation enzyme linked immunoadsorption assay (ELISA). A total of 236 patients were included in the study: 218 adults and 18 children. The mean age was 43.6 15.6 years, and the majority was males: 71.6%. The cause of renal failure was unknown in 168 patients (71.2%). The mean HD duration was 36.6 35.1 months. Prevalence of HCV seropositivity was 23.7%. Among 170 patients who were previously HCV seronegative, 30 (17.1%) seroconverted to positive in one year (estimated incidence: 63 new cases per year). HCV seropositivity was associated with longer duration of dialysis (p < 0.00001), previous surgery (p= 0.026), age of over 30 and years (p = 0.008), and dialysis in multiple centers (p= 0.005). We conclude that although HCV seropositivity in our study was lower than previously reported, it was still high among HD patients in Sudan. Nosocomial transmission of HCV among hemodialysis patients is a contributing factor.

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