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RENAL DATA FROM THE ARAB WORLD |
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Year : 2007 |
Volume
: 18 | Issue : 1 | Page
: 101-106 |
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Hepatitis C virus infection in hemodialysis patients in Sudan: Two centers' report
HH El-Amin1, EM Osman1, MO Mekki2, MB Abdelraheem1, MO Ismail1, MEA Yousif1, AM Abass2, HS El-haj1, HK Ammar3
1 Dr Salma Center for Dialysis and Kidney Transplantation, University of Khartoum, Sudan 2 Khartoum Teaching Hospital, Federal Ministry of Health, Khartoum, Sudan 3 Ahfad University for Women and Epidemiological Laboratory, Khartoum, Sudan
Correspondence Address:
M O Mekki Khartoum Teaching Hospital, Federal Ministry of Health, Khartoum Sudan
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 17237901 
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Prevalence of HCV seropositivity among the hemodialysis population in Sudan is estimated to be around 34%. We undertook a cross sectional study in two major HD centers in Khartoum, Sudan for the prevalence of HCV seropositivity among the hemodialysis patients, during January to -March 2005. Testing for HCV antibodies was performed using 3 rd generation enzyme linked immunoadsorption assay (ELISA). A total of 236 patients were included in the study: 218 adults and 18 children. The mean age was 43.6 ± 15.6 years, and the majority was males: 71.6%. The cause of renal failure was unknown in 168 patients (71.2%). The mean HD duration was 36.6 ± 35.1 months. Prevalence of HCV seropositivity was 23.7%. Among 170 patients who were previously HCV seronegative, 30 (17.1%) seroconverted to positive in one year (estimated incidence: 63 new cases per year). HCV seropositivity was associated with longer duration of dialysis (p < 0.00001), previous surgery (p= 0.026), age of over 30 and years (p = 0.008), and dialysis in multiple centers (p= 0.005). We conclude that although HCV seropositivity in our study was lower than previously reported, it was still high among HD patients in Sudan. Nosocomial transmission of HCV among hemodialysis patients is a contributing factor. |
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