Home About us Current issue Ahead of Print Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 569 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

ORIGINAL ARTICLE Table of Contents   
Year : 2010  |  Volume : 21  |  Issue : 3  |  Page : 460-465
Changes in QT intervals in patients with end-stage renal disease before and after hemodialysis

Department of Internal Medicine, Faculty of Medicine, Aleppo University Hospitals, Aleppo, Syrian Arab Republic, Syria

Correspondence Address:
Saleh Farhood
Department of Internal Medicine, Faculty of Medicine, Aleppo University Hospitals, Aleppo, Syrian Arab Republic
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 20427869

Rights and PermissionsRights and Permissions

Increased dispersion of QT intervals is known to predispose to ventricular arrhyth­mias and sudden cardiac death. To assess the effect of hemodialysis (HD) on QT and corrected QT (QTc) intervals and their dispersions in chronic hemodialyzed patients we studied 85 patients (male/female = 48/37; mean age 44 ± 17 year) on chronic hemodialysis. Simultaneous 12-lead ECG was recorded before and after HD in a standard setting. The QT intervals for each lead were measured manually by one observer using calipers. Each QT interval was corrected for heart rate: QTc= QT √ R-R/ (in milliseconds [ms]). ECG parameters, body weight, blood pressure, heart rate, electrolytes (Na + , K + , Ca ++ , phosphate), urea, and creatinine were measured before and after HD. The mean of pre and post dialysis cycle intervals was 828 ± 132 ms and 798 ± 122 ms respec­tively; the difference was not significant. The mean of QT max intervals changed significantly from 446 ± 47 to 465 ± 72 ms (P< 0.05). The mean of corrected QT cmax intervals increased significantly from 472 ± 38 to 492 ± 58 ms (P< 0.05). The mean of QT dispersions and the corrected QT interval dispersions changed from 60 ± 29 to 76 ± 32 ms (P< 0.05) from 72 ± 46 to 98 ± 56 ms (P< 0.05), respectively. During HD, the serum potassium and phosphate levels decreased whereas the calcium levels increased. We conclude that QT and QTc interval and dispersion increase in HD patients.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded827    
    Comments [Add]    
    Cited by others 6    

Recommend this journal