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Saudi Journal of Kidney Diseases and Transplantation
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ORIGINAL ARTICLE Table of Contents   
Year : 2018  |  Volume : 29  |  Issue : 4  |  Page : 816-821
Pediatric focal segmental glomerulosclerosis in Jordan: A tertiary hospital experience

1 Department of Pediatric Nephrology, Queen Rania Abdulla Children Hospital, Amman, Jordan
2 Department of Pediatric Nephrology, School of Medicine, University of Jordan, Amman, Jordan
3 Department of Nephrology, King Hussein Medical Center, Amman, Jordan

Correspondence Address:
Dr. Jumana H Albaramki
Department of Pediatric Nephrology, School of Medicine, Jordan University, P. O. Box 1459, Amman 11821
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1319-2442.239655

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Our objective is to study the demographical data, clinical course and outcome of children with primary focal segmental glomerulosclerosis (FSGS) in Jordan. A retrospective chart review of patients with a diagnosis of FSGS at a tertiary care hospital from the period July 2010 to July 2016 was conducted. A total of 99 patients were analyzed. The mean age of presentation was 3.71 ± 2.59 years, 66% were male. At presentation, 66.6% of patients were steroid-resistant, 10% had a steroid dependant course and 20.2% had familial FSGS. Cyclosporine was used in 66.6% of children with a response rate of 46.9%. Long-term follow-up showed complete remission in 29.3%, partial remission in 31.3%, end-stage renal disease in 22.2%, and death in 11.1%. There is a high prevalence of familial FSGS in our Jordanian cohort with a high rate of progression to end-stage kidney disease.

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