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| ORIGINAL ARTICLE |
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| Year : 2018 |
Volume
: 29 | Issue : 4 | Page
: 816-821 |
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Pediatric focal segmental glomerulosclerosis in Jordan: A tertiary hospital experience
Reham I Almardini1, Jumana H Albaramki2, Ghazi M Al-Saliata1, Mahdi Q Farah1, Katibah H AlRabadi3, Jawaher T Albderat1
1 Department of Pediatric Nephrology, Queen Rania Abdulla Children Hospital, Amman, Jordan
2 Department of Pediatric Nephrology, School of Medicine, University of Jordan, Amman, Jordan
3 Department of Nephrology, King Hussein Medical Center, Amman, Jordan
Correspondence Address:
Dr. Jumana H Albaramki
Department of Pediatric Nephrology, School of Medicine, Jordan University, P. O. Box 1459, Amman 11821
Jordan
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1319-2442.239655
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Our objective is to study the demographical data, clinical course and outcome of children with primary focal segmental glomerulosclerosis (FSGS) in Jordan. A retrospective chart review of patients with a diagnosis of FSGS at a tertiary care hospital from the period July 2010 to July 2016 was conducted. A total of 99 patients were analyzed. The mean age of presentation was 3.71 ± 2.59 years, 66% were male. At presentation, 66.6% of patients were steroid-resistant, 10% had a steroid dependant course and 20.2% had familial FSGS. Cyclosporine was used in 66.6% of children with a response rate of 46.9%. Long-term follow-up showed complete remission in 29.3%, partial remission in 31.3%, end-stage renal disease in 22.2%, and death in 11.1%. There is a high prevalence of familial FSGS in our Jordanian cohort with a high rate of progression to end-stage kidney disease. |
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