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| CASE REPORT |
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| Year : 2018 |
Volume
: 29 | Issue : 6 | Page
: 1502-1505 |
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Monoclonal B-cell lymphocytosis with renal involvement
Yao-Ko Wen
Department of Internal Medicine, Division of Nephrology, Changhua Christian Hospital, Changhua, Taiwan
Correspondence Address:
Dr. Yao-Ko Wen
Department of Internal Medicine, Division of Nephrology, Changhua Christian Hospital, Changhua, 500
Taiwan
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1319-2442.248281
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We report the case of a 70-year-old man with no relevant past medical history who presented with acute kidney injury. Kidney biopsy showed diffuse interstitial infiltration with typical chronic lymphocytic leukemia (CLL) phenotype B-cells. Subsequent studies revealed a normal lymphocyte count in the peripheral blood, and there was no evidence of lymphadenopathy or hepatosplenomegaly. Blood flow cytometry demonstrated a clonal B-cell population with a CLL phenotype. Without renal involvement, this case should be classified as monoclonal B-cell lymphocytosis. Renal function improved with steroid therapy. However, the patient developed CLL with significant lymphocytosis approximately two years later. |
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