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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2021  |  Volume : 32  |  Issue : 2  |  Page : 548-553
Successful chemotherapy with liposomal doxorubicin for metastatic Kaposi’s sarcoma without skin involvement in the kidney transplant recipient


1 Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice, Poland
2 Department of Nephrology, Transplantology and Internal Medicine, Medical University of Silesia, Katowice, Poland
3 Department of Pathomorphology, Medical University of Silesia, Katowice, Poland

Correspondence Address:
Jerzy Chudek
Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice
Poland
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DOI: 10.4103/1319-2442.335469

PMID: 35017351

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Kaposi’s sarcoma (KS), one of the most typical malignancies after kidney transplantation, is strongly associated with human herpes virus 8 infection. More than 90% of patients had primary skin changes, which make the diagnosis easier and faster. The lack of skin lesions is considered rare, especially in the iatrogenic type of sarcoma, including patients on immunosuppression and may cause a diagnostic challenge due to the variety of organ involvement, imitating other diseases. The aim of this case presentation is to raise attention to the atypical clinical manifestation of this malignancy. Currently, several different therapeutic options are available for patients with KS, including reduction of immunosuppression, conversion of immunosuppression to mTOR inhibitors, or chemotherapy. Here, we present an unusual case of advanced KS human immunodeficiency virus-negative patient after kidney transplantation without primary skin involvement.


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