Saudi Journal of Kidney Diseases and Transplantation

: 1998  |  Volume : 9  |  Issue : 3  |  Page : 320-

Acute Renal Failure in the Neonate

PT Subramanian 
 Hemodialysis Unit, King Fahd Central Hospital, P.O. Box 204, Gizan, Saudi Arabia

Correspondence Address:
P T Subramanian
Hemodialysis Unit, King Fahd Central Hospital, P.O. Box 204, Gizan
Saudi Arabia

How to cite this article:
Subramanian P T. Acute Renal Failure in the Neonate.Saudi J Kidney Dis Transpl 1998;9:320-320

How to cite this URL:
Subramanian P T. Acute Renal Failure in the Neonate. Saudi J Kidney Dis Transpl [serial online] 1998 [cited 2022 May 26 ];9:320-320
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To the Editor:

The article entitled acute renal failure (ARF) [1] in neonate is informative and educative. To define neonatal ARF Chevalier quotes serum creatinine concentration level.

Brocklebank [2] has mentioned that plasma creatinine concentration is of limited value in the very low birth weight infant. Moreover, Clark et al [3] did not find significant change in plasma creatinine with reference to severity of illness in neonate. From their study, they have stated that the measurement of plasma creatinine would not have detected any renal dys­function in sick babies (small group). The authors have, also suggested that urinary retinol binding protein creatinine ratio may be the most useful for detecting early renal dysfunction in neonates. Do these concepts hold good now? What is the best one? What are the limitations of each?


1Chevalier RL. Acute renal failure in the neonate. Saudi J Kidney Dis Transplant 1997;8:260-8.
2Brocklebank JT. Kidney function in very low birth weight infant (Editorial). Arch Dis Child 1992;67:1139.
3Clark PM, Bryand TN, Hall MA, et al. Neonatal renal function assessment. Arch Dis Child 1989;64:1264-9.