Saudi Journal of Kidney Diseases and Transplantation

: 2017  |  Volume : 28  |  Issue : 1  |  Page : 186--187

Zika virus infection: What should we know as nephrologists?

Beuy Joob1, Viroj Wiwanitkit2,  
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Medicine, Faculty of Medicine, University of Nis, Nis, Serbia; Department of Tropical Medicine, Hainan Medical University, Haikou, China

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok, Thailand

How to cite this article:
Joob B, Wiwanitkit V. Zika virus infection: What should we know as nephrologists?.Saudi J Kidney Dis Transpl 2017;28:186-187

How to cite this URL:
Joob B, Wiwanitkit V. Zika virus infection: What should we know as nephrologists?. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2022 Sep 28 ];28:186-187
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Full Text

To the Editor,

Emerging infectious diseases usually bring public health problems. The Zika virus infection is a new arboviral infection that is declared by the World Health Organization as a new public health threat.[1] This infection can cause acute febrile illness.[2] ,[3] It manifests as a dengue-like acute viral hemorrhagic fever.[2] ,[3] In addi-tion, it also induces fetal abnormalities if it occurs during pregnancy.[2] ,[3] To nephrologists, it is an important concern since it may cause renal problems such as the other arboviral infection, dengue.

There are many reports on the clinical presentation of the Zika virus infection. However, based on our present knowledge, there are still no reports on the renal presentation in Zika virus infection.[4] ,[5] Although it is confirmed that the virus passes through the kidney and is excreted in the urine,[6] ,[7] there is still no report on renal abnormalities among patients with Zika virus infection. A recent report investigating renal function tests in Zika virus infection showed normal results.[5] Another report from China on a patient with the Zika virus infection[5] mentioned the presence of bilateral renal calculi on renal imaging. This may be only an incidental finding. However, this finding is interesting and should be further studied. Focusing on renal pathology, autopsy studies have not shown the presence of the virus in kidney tissue.[8] ,[9] However, the problem has not been evaluated in animal models.[10] Another interesting concern is on the effect of Zika virus infection in renal transplant patients. As a new infection, there is limited knowledge on the relationship between Zika virus and transplantation-related transmission. Chan et al, recently, studied the possibility of transplantation-related transmission of the Zika virus.[4] In fact, dengue, a similar virus, has already been confirmed to have transplantationrelated transmission.[11]

We conclude that presently, there is still no evidence of renal problems in humans infected with the Zika virus. However, the topic needs further study by the nephrologists.

Conflict of interest: None declared.


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