Saudi Journal of Kidney Diseases and Transplantation

RENAL DATA FROM THE ARAB WORLD
Year
: 2017  |  Volume : 28  |  Issue : 6  |  Page : 1362--1368

The diagnosis of tuberculosis in dialysis patients


Hela Jebali1, Sana Barrah1, Lamia Rais1, Rania Kheder1, Nihal Khouja2, Salma Nadia Mhiri2, Majed Beji2, Rim Abdelmalek3, Hanene Tiouiri3, Wided Smaoui1, Soumaya Beji1, Fethi Ben Hmida4, Lilia Ben Fatma1, Mohamed Karim Zouaghi1 
1 Department of Nephrology, Dialysis and Transplantation, Tunis, Tunisia
2 Department of Pneumology, La Rabta Hospital, Tunis, Tunisia
3 Department of Infectiology, La Rabta Hospital, Tunis, Tunisia
4 Department of Research Laboratory of Kidney Diseases (LR00SP01), Charles Nicolle Hospital; Department of Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia

Correspondence Address:
Sana Barrah
Department of Nephrology, Dialysis and Transplantation, La Rabta Hospital, Tunis
Tunisia

The incidence of tuberculosis (TB) is high in patients undergoing chronic dialysis than it is in the general population. The diagnosis of TB is often difficult and extrapulmonary involvement is predominant. This study investigates the spectrum of clinical presentations and outcome in dialysis patients during a nine-year period. TB was diagnosed in 41 patients. Anti-TB drugs, adverse effects of therapy, and outcome were noted. Thirty-eight patients (92.6%) were on hemodialysis and three were on peritoneal dialysis (7.3%). The mean age at diagnosis was 50.8 years and the male/female ratio was 1.16. Four patients had a history of pulmonary TB. Extrapulmonary involvement was observed in 32 (78 %) patients. The bacteriological confirmation was made in 41.46% and histological confirmation was made in 26.83%, and in the rest, the diagnosis was retained on the criterion presumption. Nineteen patients (46.34%) developed adverse effects of antitubercular drugs. Eight patients (19.51%) died during the study from TB or adverse effects of treatment. Low urea reduction ratio and female sex were associated with poor prognosis in our study. The clinical manifestations of TB in patients on dialysis are quite nonspecific, making timely diagnosis difficult, and delaying the initiation of curative treatment, which is a major determinant of the outcome.


How to cite this article:
Jebali H, Barrah S, Rais L, Kheder R, Khouja N, Mhiri SN, Beji M, Abdelmalek R, Tiouiri H, Smaoui W, Beji S, Hmida FB, Fatma LB, Zouaghi MK. The diagnosis of tuberculosis in dialysis patients.Saudi J Kidney Dis Transpl 2017;28:1362-1368


How to cite this URL:
Jebali H, Barrah S, Rais L, Kheder R, Khouja N, Mhiri SN, Beji M, Abdelmalek R, Tiouiri H, Smaoui W, Beji S, Hmida FB, Fatma LB, Zouaghi MK. The diagnosis of tuberculosis in dialysis patients. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2022 May 24 ];28:1362-1368
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=6;spage=1362;epage=1368;aulast=Jebali;type=0