Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2018  |  Volume : 29  |  Issue : 3  |  Page : 719--722

Multiple tuberculomas invading the central nervous system as a paradoxical reaction in a kidney transplantation recipient


Yaerim Kim1, Sang Pyo Kim2, Seungyeup Han3 
1 Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
2 Department of Pathology, Keimyung University School of Medicine, Daegu, Korea
3 Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institution, Daegu, Korea

Correspondence Address:
Dr. Seungyeup Han
Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institute, Jung-gu, Daegu 41931
Korea

A paradoxical reaction during anti-tuberculosis (anti-TB) therapy is commonly reported in patients with human immunodeficiency virus (HIV). However, a similar reaction to anti-TB therapy can also occur in patients without HIV, especially in patients who have undergone solid organ transplantation. A 65-year-old woman who underwent kidney transplantation six months prior presented to our emergency room with progressive paraparesis. She had been diagnosed with drug-susceptible miliary TB and had undergone two weeks of treatment with anti-TB medication. Magnetic resonance imaging showed a spinal intramedullary mass and multiple intracranial nodules. The etiology of the lesions was confirmed as Mycobacterium tuberculosis. We report a paradoxical reaction of spinal intramedullary and multiple intracranial tuberculomas in a patient with miliary TB who had received appropriate treatment for more than two weeks.


How to cite this article:
Kim Y, Kim SP, Han S. Multiple tuberculomas invading the central nervous system as a paradoxical reaction in a kidney transplantation recipient.Saudi J Kidney Dis Transpl 2018;29:719-722


How to cite this URL:
Kim Y, Kim SP, Han S. Multiple tuberculomas invading the central nervous system as a paradoxical reaction in a kidney transplantation recipient. Saudi J Kidney Dis Transpl [serial online] 2018 [cited 2022 Aug 9 ];29:719-722
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2018;volume=29;issue=3;spage=719;epage=722;aulast=Kim;type=0