Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 32  |  Issue : 2  |  Page : 318--327

Acute kidney injury in patients with ST-segment elevation acute myocardial infarction: Predictors and outcomes


Evgeny Mikhailovich Mezhonov1, Iuliia Aleksandrovna Vialkina2, Kristina Aleksandrovna Vakulchik1, Sergey Vasilevich Shalaev1 
1 GBUZ TO “Regional Clinical Hospital No. 1”; Department of Cardiology and Cardiac Surgery, Federal State Budgetary Educational Institution of Higher Education Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation, Tyumen, Russia
2 Department of Hospital Therapy, Federal State Budgetary Educational Institution of Higher Education Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation, Tyumen, Russia

Correspondence Address:
Evgeny Mikhailovich Mezhonov
GBUZ TO “Regional Clinical Hospital No. 1”, Tyumen
Russia

The development of acute kidney injury (AKI) in patients during hospitalization worsens the prognosis. The study aimed to estimate the prognostic value of AKI in patients with ST-segment elevation myocardial infarction (MI) in prospective follow-up study. A prospective follow-up of 12 months included 268 patients with ST-segment elevation MI who underwent percutaneous coronary intervention. The incidence of AKI was assessed and its effect on the outcome of ST-segment elevation MI during the observed period was traced. AKI was diagnosed according to Kidney Disease: Improving Global Outcomes recommendations. AKI was recorded in 20.5%. The incidence of AKI increased with decrease in the level of glomerular filtration rate on admission (P = 0.047) and an increase in the stage of acute heart failure according to Killip on admission (P = 0.006). The development of AKI was associated with an increase in-hospital mortality, increasing with a worsening stage of AKI (P<0.001), the same pattern was characteristic for death from cardiovascular causes during follow-up. AKI increases the risk of death from cardiovascular causes by four times [odds ratio 95% 4.400 (1.928–10.040), P <0.001]. The multivariate analysis revealed risk factors for the development of AKI: age >75 years (P = 0.006), female (P = 0.008), Killip >I (P = 0.045). AKI is common in patients with ST-segment elevation MI and is associated with a poor prognosis. The development of AKI is associated with an increase mortality, increasing with a worsening stage of AKI.


How to cite this article:
Mezhonov EM, Vialkina IA, Vakulchik KA, Shalaev SV. Acute kidney injury in patients with ST-segment elevation acute myocardial infarction: Predictors and outcomes.Saudi J Kidney Dis Transpl 2021;32:318-327


How to cite this URL:
Mezhonov EM, Vialkina IA, Vakulchik KA, Shalaev SV. Acute kidney injury in patients with ST-segment elevation acute myocardial infarction: Predictors and outcomes. Saudi J Kidney Dis Transpl [serial online] 2021 [cited 2022 May 26 ];32:318-327
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=2;spage=318;epage=327;aulast=Mezhonov;type=0