Saudi Journal of Kidney Diseases and Transplantation

REVIEW ARTICLE
Year
: 2021  |  Volume : 32  |  Issue : 6  |  Page : 1511--1522

Dietary Acid Load and Chronic Kidney Disease


Maryam Hamidianshirazi1, Maryam Ekramzadeh2 
1 Student Research Committee; Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
2 Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran; Division of Nephrology and Hypertension at the Lundquist Institute at Harbor-UCLA Center Torrance, California, USA, Iran

Correspondence Address:
Maryam Ekramzadeh
Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran

Chronic kidney disease (CKD) is a condition in which kidneys are damaged and can not function well, so this leads to the aggregation of excessive fluid and waste products in the blood. The acidity and alkalinity of urine are affected by our daily diet. Dietary proteins, especially amino acids containing sulfur (e.g., methionine and cysteine), are the major determinants of the dietary acid load because they can produce sulfate due to oxidation. Diet can affect the excreted acidity through the kidneys to maintain the acid-base balance. Diets with animal protein content contain more precursor acids than basic precursors compared to fruits and vegetables that produce more acid in the body than animal proteins and dramatically affect CKD and its progression. Acid-producing diets can cause high blood pressure through the kidneys, causing the production of the hormones angiotensin II, endothelin-1, and aldosterone. Metabolic acidosis can cause CKD and reduced bone tissue.


How to cite this article:
Hamidianshirazi M, Ekramzadeh M. Dietary Acid Load and Chronic Kidney Disease.Saudi J Kidney Dis Transpl 2021;32:1511-1522


How to cite this URL:
Hamidianshirazi M, Ekramzadeh M. Dietary Acid Load and Chronic Kidney Disease. Saudi J Kidney Dis Transpl [serial online] 2021 [cited 2022 Aug 16 ];32:1511-1522
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=6;spage=1511;epage=1522;aulast=Hamidianshirazi;type=0