Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2021  |  Volume : 32  |  Issue : 6  |  Page : 1804--1808

Acute Kidney Injury and Nephrotic Syndrome in Guillain-Barre Syndrome: A Rare Clinical Scenario


M. P. Shamsudheen, Sarang Vijayan, Abid Kuchay, Gangadhar Taduri, Swarnalatha Guditi, Raja Karthik, Uttara Das 
 Department of Nephrology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India

Correspondence Address:
Gangadhar Taduri
Department of Nephrology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India.
India

Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy, caused by dysregulated immune response following an infectious or noninfectious event. Although cardiovascular, respiratory, and gastrointestinal systems are commonly involved secondary to neuromuscular paralysis, renal manifestations are rare. Acute kidney injury (AKI) can develop in GBS due to acute tubular necrosis secondary to dysautonomia. Minimal change nephrotic syndrome in GBS may be due to T-cell dysregulation and cytokine release attributed to molecular mimicry. Here, we report the case of GBS with simultaneously developed AKI and nephrotic syndrome during the course of disease, which recovered completely in parallel with neurological improvement without any immunosuppressive medications.


How to cite this article:
Shamsudheen MP, Vijayan S, Kuchay A, Taduri G, Guditi S, Karthik R, Das U. Acute Kidney Injury and Nephrotic Syndrome in Guillain-Barre Syndrome: A Rare Clinical Scenario.Saudi J Kidney Dis Transpl 2021;32:1804-1808


How to cite this URL:
Shamsudheen MP, Vijayan S, Kuchay A, Taduri G, Guditi S, Karthik R, Das U. Acute Kidney Injury and Nephrotic Syndrome in Guillain-Barre Syndrome: A Rare Clinical Scenario. Saudi J Kidney Dis Transpl [serial online] 2021 [cited 2022 Sep 25 ];32:1804-1808
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=6;spage=1804;epage=1808;aulast=Shamsudheen;type=0